Hi Andy, I tried the Master Cleanse once (just once!) and don’t claim to have received any miraculous benefit from it. However, I will say that the experience of going without meals and my usual food routines was extremely confrontational. What! No morning coffee! What! No wine before dinner — and no dinner! Wait! No midday meal to break my work hours? No snack? It provided me with an opportunity to examine my eating in a pretty dramatic way. For that reason alone, I think trying a fast once isn’t such a bad idea.